Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison

There is an interest in identifying Anaphase Promoting-Complex/Cyclosome (APC/C) inhibitors that lead to sensitivity to microtubule poisons as a strategy for targeting cancer cells. Using budding yeast Saccharomyces cerevisiae, peptides derived from the Mitotic Arrest Deficient 2 (Mad2)-binding moti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schuyler, Scott C., Wu, Yueh-Fu Olivia, Chen, Hsin-Yu, Ding, Yi-Shan, Lin, Chia-Jung, Chu, Yu-Ting, Chen, Ting-Chun, Liao, Louis, Tsai, Wei-Wei, Huang, Anna, Wang, Lin-Ing, Liao, Ting-Wei, Jhuo, Jia-Hua, Cheng, Vivien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993284/
https://ncbi.nlm.nih.gov/pubmed/29883473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198930
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