Calling on the cancer sleuths: how cell biologists will do the detective legwork of the postcancer genome era

by Trotman, Lloyd C.
Published 2011

PTEN Plasticity - How the Taming of a Lethal Gene Can Go too Far

by Naguib, Adam, Trotman, Lloyd C.
Published 2013

Competence against insufficiency: Why are men mostly safe from a rare and deadly prostate cancer?

by Mathew, Grinu, Trotman, Lloyd C.
Published in J Exp Med (2020)

Turning Off AKT: PHLPP as a Drug Target

by Newton, Alexandra C., Trotman, Lloyd C.
Published 2014

PTEN: Bridging Endocytosis and Signaling

by Lee, Matthew F., Trotman, Lloyd C.
Published in Cold Spring Harb Perspect Med (2020)

Molecular Pathways: PI 3-Kinase Pathway Phosphatases as Biomarkers for Cancer Prognosis and Therapy

by Chen, Muhan, Nowak, Dawid G., Trotman, Lloyd C.
Published 2014

Nuclear Targeting of Adenovirus Type 2 Requires CRM1-mediated Nuclear Export

by Strunze, Sten, Trotman, Lloyd C., Boucke, Karin, Greber, Urs F.
Published 2005

PTEN Regulation of Local and Long-Range Connections in Mouse Auditory Cortex

by Xiong, Qiaojie, Oviedo, Hysell V., Trotman, Lloyd C., Zador, Anthony M.
Published 2012

Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome

by Cho, Hyejin, Stahlhut, Carlos, Herzka, Tali, Watrud, Kaitlin, Robinson, Brian D., Trotman, Lloyd C.
Published in Methods (2015)

Identification of a tumour suppressor network opposing nuclear Akt function

by Trotman, Lloyd C., Alimonti, Andrea, Scaglioni, Pier Paolo, Koutcher, Jason A., Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Published 2006

Prostate cancer genetic-susceptibility locus on chromosome 20q13 is androgen receptor-regulated and amplified in metastatic tumors

by Labbé, David P., Nowak, Dawid G., Deblois, Geneviève, Lessard, Laurent, Giguère, Vincent, Trotman, Lloyd C., Tremblay, Michel L.
Published 2013

Mutations in p53 change phosphatidylinositol acyl chain composition

by Naguib, Adam, Bencze, Gyula, Engle, Dannielle, Chio, Iok I. C., Herzka, Tali, Watrud, Kaitlin, Bencze, Szilvia, Tuveson, David A., Pappin, Darryl J, Trotman, Lloyd C.
Published in Cell Rep (2014)

Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization

by Senturk, Serif, Shirole, Nitin H., Nowak, Dawid G., Corbo, Vincenzo, Pal, Debjani, Vaughan, Alexander, Tuveson, David A., Trotman, Lloyd C., Kinney, Justin B., Sordella, Raffaella
Published in Nat Commun (2017)

RapidCaP, a novel GEM model for analysis and therapy of metastatic prostate cancer reveals Myc as a driver of Pten-mutant metastasis

by Cho, Hyejin, Herzka, Tali, Zheng, Wu, Qi, Jun, Wilkinson, John E., Bradner, James E., Robinson, Brian D., Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Trotman, Lloyd C.
Published 2014

PTP1B deficiency enables the ability of a high fat diet to drive the invasive character of PTEN-deficient prostate cancers

by Labbé, David P., Uetani, Noriko, Vinette, Valérie, Lessard, Laurent, Aubry, Isabelle, Migon, Eva, Sirois, Jacinthe, Haigh, Jody J., Bégin, Louis R., Trotman, Lloyd C., Paquet, Marilène, Tremblay, Michel L.
Published in Cancer Res (2016)

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

by Chen, Zhenbang, Trotman, Lloyd C., Shaffer, David, Lin, Hui-Kuan, Dotan, Zohar A., Niki, Masaru, Koutcher, Jason A., Scher, Howard I., Ludwig, Thomas, Gerald, William, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Published 2005

Subtle variations in Pten dose determine cancer susceptibility

by Alimonti, Andrea, Carracedo, Arkaitz, Clohessy, John G, Trotman, Lloyd C, Nardella, Caterina, Egia, Ainara, Salmena, Leonardo, Sampieri, Katia, Haveman, William J, Brogi, Edi, Richardson, Andrea L, Zhang, Jiangwen, Pandolfi, Pier Paolo
Published 2010

Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output

by Reyes, Gloria, Niederst, Matt, Cohen-Katsenelson, Ksenya, Stender, Joshua D., Kunkel, Maya T., Chen, Muhan, Brognard, John, Sierecki, Emma, Gao, Tianyan, Nowak, Dawid G., Trotman, Lloyd C., Glass, Christopher K., Newton, Alexandra C.
Published 2014

Pten Dose Dictates Cancer Progression in the Prostate

by Trotman, Lloyd C, Niki, Masaru, Dotan, Zohar A, Koutcher, Jason A, Di Cristofano, Antonio, Xiao, Andrew, Khoo, Alan S, Roy-Burman, Pradip, Greenberg, Norman M, Dyke, Terry Van, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Published 2003

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

by Alimonti, Andrea, Nardella, Caterina, Chen, Zhenbang, Clohessy, John G., Carracedo, Arkaitz, Trotman, Lloyd C., Cheng, Ke, Varmeh, Shohreh, Kozma, Sara C., Thomas, George, Rosivatz, Erika, Woscholski, Rudiger, Cognetti, Francesco, Scher, Howard I., Pandolfi, Pier Paolo
Published 2010