Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output

Growth factor receptor levels are aberrantly high in diverse cancers, driving the proliferation and survival of tumor cells. Understanding the molecular basis for this aberrant elevation has profound clinical implications. Here we show that the pleckstrin homology domain leucine-rich repeat protein...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Reyes, Gloria, Niederst, Matt, Cohen-Katsenelson, Ksenya, Stender, Joshua D., Kunkel, Maya T., Chen, Muhan, Brognard, John, Sierecki, Emma, Gao, Tianyan, Nowak, Dawid G., Trotman, Lloyd C., Glass, Christopher K., Newton, Alexandra C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183331/
https://ncbi.nlm.nih.gov/pubmed/25201979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404221111
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker