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Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase (PHLPP): A New Player in Cell Signaling

Precise balance between phosphorylation, catalyzed by protein kinases, and dephosphorylation, catalyzed by protein phosphatases, is essential for cellular homeostasis. Deregulation of this balance leads to pathophysiological states that drive diseases such as cancer, heart disease, and diabetes. The...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Warfel, Noel A., Newton, Alexandra C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281723/
https://ncbi.nlm.nih.gov/pubmed/22144674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.318675
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