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Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C

The proper establishment of epithelial polarity allows cells to sense and respond to signals that arise from the microenvironment in a spatiotemporally controlled manner. Atypical PKCs (aPKCs) are implicated as key regulators of epithelial polarity. However, the molecular mechanism underlying the ne...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Xiong, Xiaopeng, Li, Xin, Wen, Yang-An, Gao, Tianyan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122783/
https://ncbi.nlm.nih.gov/pubmed/27760826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740639
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