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Prostate cancer genetic-susceptibility locus on chromosome 20q13 is androgen receptor-regulated and amplified in metastatic tumors

The 20q13 chromosomal region has been previously identified as the hereditary prostate cancer genetic-susceptibility locus on chromosome 20 (HPC20). In this study, we demonstrate that this region is also frequently co-amplified with the androgen receptor (AR) in metastatic prostate cancer. We show t...

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Detalhes bibliográficos
Main Authors: Labbé, David P., Nowak, Dawid G., Deblois, Geneviève, Lessard, Laurent, Giguère, Vincent, Trotman, Lloyd C., Tremblay, Michel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944382/
https://ncbi.nlm.nih.gov/pubmed/24379448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0477
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