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PTP1B is an androgen receptor-regulated phosphatase associated with tumor-promoting functions in prostate cancer

The androgen receptor (AR)-signaling axis plays a key role in the pathogenesis of prostate cancer. The identification of AR targets contributing to prostate tumorigenesis is thus critical for the development of more effective therapies. Herein, we examined whether the AR could regulate classical pro...

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Библиографические подробности
Опубликовано в: :Cancer Res
Главные авторы: Lessard, Laurent, Labbé, David P., Deblois, Geneviève, Bégin, Louis R., Hardy, Serge, Mes-Masson, Anne-Marie, Saad, Fred, Trotman, Lloyd, Giguère, Vincent, Tremblay, Michel L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080984/
https://ncbi.nlm.nih.gov/pubmed/22282656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2602
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