Reverse genetics in eukaryotes

Por Hardy, Serge, Legagneux, Vincent, Audic, Yann, Paillard, Luc
Publicado em 2010

Polypyrimidine Tract Binding Protein Prevents Activity of an Intronic Regulatory Element That Promotes Usage of a Composite 3′-Terminal Exon

Por Anquetil, Vincent, Le Sommer, Caroline, Méreau, Agnès, Hamon, Sandra, Lerivray, Hubert, Hardy, Serge
Publicado em 2009

PTB Regulates the Processing of a 3′-Terminal Exon by Repressing both Splicing and Polyadenylation

Por Le Sommer, Caroline, Lesimple, Michelle, Mereau, Agnès, Menoret, Severine, Allo, Marie-Rose, Hardy, Serge
Publicado em 2005

Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse

Por Hassan, Syed-Wajahat, Doody, Karen M., Hardy, Serge, Uetani, Noriko, Cournoyer, Denis, Tremblay, Michel L.
Publicado em 2010

Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Por Wu, Chia-Lun, Hardy, Serge, Aubry, Isabelle, Landry, Melissa, Haggarty, Allison, Saragovi, Horacio Uri, Tremblay, Michel L.
Publicado no PLoS One (2017)

A Posttranscriptional Mechanism That Controls Ptbp1 Abundance in the Xenopus Epidermis

Por Méreau, Agnès, Anquetil, Vincent, Lerivray, Hubert, Viet, Justine, Schirmer, Claire, Audic, Yann, Legagneux, Vincent, Hardy, Serge, Paillard, Luc
Publicado no Mol Cell Biol (2015)

A Two-amino Acid Mutation Encountered in Duchenne Muscular Dystrophy Decreases Stability of the Rod Domain 23 (R23) Spectrin-like Repeat of Dystrophin

Por Legardinier, Sébastien, Legrand, Baptiste, Raguénès-Nicol, Céline, Bondon, Arnaud, Hardy, Serge, Tascon, Christophe, Le Rumeur, Elisabeth, Hubert, Jean-François
Publicado em 2009

Caspase-3 Regulates Catalytic Activity and Scaffolding Functions of the Protein Tyrosine Phosphatase PEST, a Novel Modulator of the Apoptotic Response

Por Hallé, Maxime, Liu, Ying-Chih, Hardy, Serge, Théberge, Jean-François, Blanchetot, Christophe, Bourdeau, Annie, Meng, Tzu-Ching, Tremblay, Michel L.
Publicado em 2007

PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms

Por Uetani, Noriko, Hardy, Serge, Gravel, Simon-Pierre, Kiessling, Silke, Pietrobon, Adam, Wong, Nau Nau, Chénard, Valérie, Cermakian, Nicolas, St-Pierre, Julie, Tremblay, Michel L.
Publicado no JCI Insight (2017)

PTP1B is an androgen receptor-regulated phosphatase associated with tumor-promoting functions in prostate cancer

Por Lessard, Laurent, Labbé, David P., Deblois, Geneviève, Bégin, Louis R., Hardy, Serge, Mes-Masson, Anne-Marie, Saad, Fred, Trotman, Lloyd, Giguère, Vincent, Tremblay, Michel L.
Publicado no Cancer Res (2012)

Inhibition of PRL-2·CNNM3 Protein Complex Formation Decreases Breast Cancer Proliferation and Tumor Growth

Por Kostantin, Elie, Hardy, Serge, Valinsky, William C., Kompatscher, Andreas, de Baaij, Jeroen H. F., Zolotarov, Yevgen, Landry, Melissa, Uetani, Noriko, Martínez-Cruz, Luis Alfonso, Hoenderop, Joost G. J., Shrier, Alvin, Tremblay, Michel L.
Publicado no J Biol Chem (2016)

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2

Por Giménez-Mascarell, Paula, Oyenarte, Iker, Hardy, Serge, Breiderhoff, Tilman, Stuiver, Marchel, Kostantin, Elie, Diercks, Tammo, Pey, Angel L., Ereño-Orbea, June, Martínez-Chantar, María Luz, Khalaf-Nazzal, Reham, Claverie-Martin, Felix, Müller, Dominik, Tremblay, Michel L., Martínez-Cruz, Luis Alfonso
Publicado no J Biol Chem (2017)