Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPG), which can modulate RPTPσ activity b...

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Publicado en:PLoS One
Autores principales: Wu, Chia-Lun, Hardy, Serge, Aubry, Isabelle, Landry, Melissa, Haggarty, Allison, Saragovi, Horacio Uri, Tremblay, Michel L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449173/
https://ncbi.nlm.nih.gov/pubmed/28558026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178489
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