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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPG), which can modulate RPTPσ activity b...

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書目詳細資料
發表在:PLoS One
Main Authors: Wu, Chia-Lun, Hardy, Serge, Aubry, Isabelle, Landry, Melissa, Haggarty, Allison, Saragovi, Horacio Uri, Tremblay, Michel L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449173/
https://ncbi.nlm.nih.gov/pubmed/28558026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178489
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