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Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.

T cell protein tyrosine phosphatase (TC-PTP/PTPN2) is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. We previously observed that TC-PTP(-/-) mice display various immunodeficiencies, hypersensit...

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Bibliographic Details
Main Authors: Syed-Wajahat Hassan, Karen M Doody, Serge Hardy, Noriko Uetani, Denis Cournoyer, Michel L Tremblay
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2810325?pdf=render
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