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Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse

T cell protein tyrosine phosphatase (TC-PTP / PTPN2) is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. We previously observed that TC-PTP(−/−) mice display various immunodeficiencies, hypersens...

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Autors principals: Hassan, Syed-Wajahat, Doody, Karen M., Hardy, Serge, Uetani, Noriko, Cournoyer, Denis, Tremblay, Michel L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810325/
https://ncbi.nlm.nih.gov/pubmed/20111595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008868
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