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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPG), which can modulate RPTPσ activity b...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wu, Chia-Lun, Hardy, Serge, Aubry, Isabelle, Landry, Melissa, Haggarty, Allison, Saragovi, Horacio Uri, Tremblay, Michel L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449173/
https://ncbi.nlm.nih.gov/pubmed/28558026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178489
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