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Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain

Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate proteoglycans (HSPG), which can modulate RPTPσ activity b...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wu, Chia-Lun, Hardy, Serge, Aubry, Isabelle, Landry, Melissa, Haggarty, Allison, Saragovi, Horacio Uri, Tremblay, Michel L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449173/
https://ncbi.nlm.nih.gov/pubmed/28558026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178489
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