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Nuclear Targeting of Adenovirus Type 2 Requires CRM1-mediated Nuclear Export

Incoming adenovirus type 2 (Ad2) and Ad5 shuttle bidirectionally along microtubules, biased to the microtubule-organizing center by the dynein/dynactin motor complex. It is unknown how the particles reach the nuclear pore complex, where capsids disassemble and viral DNA enters the nucleus. Here, we...

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Bibliografiske detaljer
Main Authors: Strunze, Sten, Trotman, Lloyd C., Boucke, Karin, Greber, Urs F.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142442/
https://ncbi.nlm.nih.gov/pubmed/15814838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-02-0121
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