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Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus
Nuclear targeting of adenovirus is mediated by the microtubule-dependent, minus-end-directed motor complex dynein/dynactin, in competition with plus- end-directed motility. We demonstrate that adenovirus transiently activates two distinct signaling pathways to enhance nuclear targeting. The first pa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145525/ https://ncbi.nlm.nih.gov/pubmed/11250897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1310 |
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