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Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus

Nuclear targeting of adenovirus is mediated by the microtubule-dependent, minus-end-directed motor complex dynein/dynactin, in competition with plus- end-directed motility. We demonstrate that adenovirus transiently activates two distinct signaling pathways to enhance nuclear targeting. The first pa...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Suomalainen, M., Nakano, M.Y., Boucke, K., Keller, S., Greber, U.F.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.6.1310
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