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Cholesterol Is Required for Endocytosis and Endosomal Escape of Adenovirus Type 2
The species C adenovirus type 2 (Ad2) and Ad5 bind the coxsackievirus B Ad receptor and αv integrin coreceptors and enter epithelial cells by clathrin-mediated endocytosis. This pathway is rapid and efficient. It leads to cell activation and the cholesterol-dependent formation of macropinosomes. Mac...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC353764/ https://ncbi.nlm.nih.gov/pubmed/14990728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3089-3098.2004 |
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