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Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection.

A recent theory suggests that endocytosis is involved in uptake and intracellular transport of electrotransfected plasmid DNA (pDNA). The goal of the current study was to understand if approaches used previously to improve endocytosis of gene delivery vectors could be applied to enhancing electrotra...

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Autori principali: Lisa D Cervia, Chun-Chi Chang, Liangli Wang, Fan Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171699&type=printable
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