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Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection.

A recent theory suggests that endocytosis is involved in uptake and intracellular transport of electrotransfected plasmid DNA (pDNA). The goal of the current study was to understand if approaches used previously to improve endocytosis of gene delivery vectors could be applied to enhancing electrotra...

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Autores principales: Lisa D Cervia, Chun-Chi Chang, Liangli Wang, Fan Yuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Colección:PLoS ONE
Acceso en línea:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171699&type=printable
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