Cholesterol Is Required for Endocytosis and Endosomal Escape of Adenovirus Type 2

The species C adenovirus type 2 (Ad2) and Ad5 bind the coxsackievirus B Ad receptor and αv integrin coreceptors and enter epithelial cells by clathrin-mediated endocytosis. This pathway is rapid and efficient. It leads to cell activation and the cholesterol-dependent formation of macropinosomes. Mac...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Imelli, Nicola, Meier, Oliver, Boucke, Karin, Hemmi, Silvio, Greber, Urs F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2004
Fag:	Replication
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.3089-3098.2004
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