The Future of Interleukin-2: Enhancing Therapeutic Anticancer Vaccines

Por Overwijk, Willem W., Theoret, Marc R., Restifo, Nicholas P.
Publicado em 2000

Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

Por Shrimali, Rajeev K., Yu, Zhiya, Theoret, Marc R., Chinnasamy, Dhanalakshmi, Restifo, Nicholas P., Rosenberg, Steven A.
Publicado em 2010

Development of Human Anti-Murine T-cell Receptor Antibodies in Both Responding and Non-responding Patients Enrolled in TCR Gene Therapy Trials

Por Davis, Jeremy L., Theoret, Marc R., Zheng, Zhili, Lamers, Cor, Rosenberg, Steven A., Morgan, Richard A.
Publicado em 2010

Assumptions of the tumor ‘escape’ hypothesis

Por Restifo, Nicholas P., Antony, Paul A., Finkelstein, Steven E., Leitner, Wolfgang W., Surman, Deborah R., Theoret, Marc R., Touloukian, Christopher E.
Publicado em 2002

Cross-priming utilizes antigen not available to the direct presentation pathway

Por Donohue, Keri B, Grant, Jean M, Tewalt, Eric F, Palmer, Douglas C, Theoret, Marc R, Restifo, Nicholas P, Norbury, Christopher C
Publicado em 2006

Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

Por Chinnasamy, Dhanalakshmi, Yu, Zhiya, Theoret, Marc R., Zhao, Yangbing, Shrimali, Rajeev K., Morgan, Richard A., Feldman, Steven A., Restifo, Nicholas P., Rosenberg, Steven A.
Publicado em 2010

Poor immunogenicity of a self/tumor antigen derives from peptide–MHC-I instability and is independent of tolerance

Por Yu, Zhiya, Theoret, Marc R., Touloukian, Christopher E., Surman, Deborah R., Garman, Scott C., Feigenbaum, Lionel, Baxter, Tiffany K., Baker, Brian M., Restifo, Nicholas P.
Publicado em 2004

CTLA-4 dysregulation of self/tumor-reactive CD8(+) T-cell function is CD4(+) T-cell dependent

Por Gattinoni, Luca, Ranganathan, Anju, Surman, Deborah R., Palmer, Douglas C., Antony, Paul A., Theoret, Marc R., Heimann, David M., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2006

Regulation of immunotherapeutic products for cancer and FDA’s role in product development and clinical evaluation

Por Vatsan, Ramjay S, Bross, Peter F, Liu, Ke, Theoret, Marc, De Claro, Angelo R, Lu, Jinhua, Helms, Whitney, Niland, Brian, Husain, Syed R, Puri, Raj K
Publicado em 2013

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8(+) T cells

Por Gattinoni, Luca, Klebanoff, Christopher A., Palmer, Douglas C., Wrzesinski, Claudia, Kerstann, Keith, Yu, Zhiya, Finkelstein, Steven E., Theoret, Marc R., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

Relationship of p53 Overexpression on Cancers and Recognition by Anti-p53 T Cell Receptor-Transduced T Cells

Por Theoret, Marc R., Cohen, Cyrille J., Nahvi, Azam V., Ngo, Lien T., Suri, Kimberly B., Powell, Daniel J., Dudley, Mark E., Morgan, Richard A., Rosenberg, Steven A.
Publicado em 2008

High Efficiency TCR Gene Transfer into Primary Human Lymphocytes Affords Avid Recognition of Melanoma Tumor Antigen Glycoprotein 100 and Does Not Alter the Recognition of Autologou...

Por Morgan, Richard A., Dudley, Mark E., Yu, Yik Y. L., Zheng, Zhili, Robbins, Paul F., Theoret, Marc R., Wunderlich, John R., Hughes, Marybeth S., Restifo, Nicholas P., Rosenberg, Steven A.
Publicado em 2003

Vaccine-Stimulated, Adoptively Transferred CD8(+) T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction

Por Palmer, Douglas C., Balasubramaniam, Sanjeeve, Hanada, Ken-ichi, Wrzesinski, Claudia, Yu, Zhiya, Farid, Shahram, Theoret, Marc R., Hwang, Leroy N., Klebanoff, Christopher A., Gattinoni, Luca, Goldstein, Allan L., Yang, James C., Restifo, Nicholas P.
Publicado em 2004

TSCOT (+) Thymic Epithelial Cell-Mediated Sensitive CD4 Tolerance by Direct Presentation

Por Ahn, Sejin, Lee, Gwanghee, Yang, Soo Jung, Lee, Deokjae, Lee, Seunghyuk, Shin, Hyo Sun, Kim, Min Cheol, Lee, Kee Nyung, Palmer, Douglas C, Theoret, Marc R, Jenkinson, Eric J, Anderson, Graham, Restifo, Nicholas P, Kim, Moon Gyo
Publicado em 2008

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8(+) T Cells

Por Klebanoff, Christopher A., Finkelstein, Steven E., Surman, Deborah R., Lichtman, Michael K., Gattinoni, Luca, Theoret, Marc R., Grewal, Navrose, Spiess, Paul J., Antony, Paul A., Palmer, Douglas C., Tagaya, Yutaka, Rosenberg, Steven A., Waldmann, Thomas A., Restifo, Nicholas P.
Publicado em 2004

Immunological and Antitumor Effects of IL-23 as a Cancer Vaccine Adjuvant

Por Overwijk, Willem W., de Visser, Karin E., Tirion, Felicia H., de Jong, Laurina A., Pols, Thijs W. H., Velden, Yme U. van der, Boorn, Jasper G. van den, Keller, Anna M., Buurman, Wim A., Theoret, Marc R., Blom, Bianca, Restifo, Nicholas P., Kruisbeek, Ada M., Kastelein, Robert A., Haanen, John B. A. G.
Publicado em 2006

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8(+) T Cells

Por Overwijk, Willem W., Theoret, Marc R., Finkelstein, Steven E., Surman, Deborah R., de Jong, Laurina A., Vyth-Dreese, Florry A., Dellemijn, Trees A., Antony, Paul A., Spiess, Paul J., Palmer, Douglas C., Heimann, David M., Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Feigenbaum, Lionel, Kruisbeek, Ada M., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2003