Relationship of p53 Overexpression on Cancers and Recognition by Anti-p53 T Cell Receptor-Transduced T Cells

Tumor suppressor p53 is reported to be an attractive immunotherapy target because it is mutated in approximately half of human cancers, resulting in inactivation and often an accumulation of the protein in the tumor cells. Only low amounts of protein are detectable in normal tissues. The differentia...

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Detalhes bibliográficos
Main Authors: Theoret, Marc R., Cohen, Cyrille J., Nahvi, Azam V., Ngo, Lien T., Suri, Kimberly B., Powell, Daniel J., Dudley, Mark E., Morgan, Richard A., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Scientific Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889139/
https://ncbi.nlm.nih.gov/pubmed/19848582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.083
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