Relationship of p53 Overexpression on Cancers and Recognition by Anti-p53 T Cell Receptor-Transduced T Cells

Tumor suppressor p53 is reported to be an attractive immunotherapy target because it is mutated in approximately half of human cancers, resulting in inactivation and often an accumulation of the protein in the tumor cells. Only low amounts of protein are detectable in normal tissues. The differentia...

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Autors principals: Theoret, Marc R., Cohen, Cyrille J., Nahvi, Azam V., Ngo, Lien T., Suri, Kimberly B., Powell, Daniel J., Dudley, Mark E., Morgan, Richard A., Rosenberg, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2008
Matèries:
Scientific Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889139/
https://ncbi.nlm.nih.gov/pubmed/19848582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.083
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