Cannabinoid Receptor 1 Positive Allosteric Modulators for Posttraumatic Stress Disorder

di Shekhar, Anantha, Thakur, Ganesh A
Pubblicato in Neuropsychopharmacology (2018)

Microwave-assisted Expeditious and Efficient Synthesis of Cyclopentene Ring-fused Tetrahydroquinoline Derivatives Using Three-component Povarov Reaction

di Kulkarni, Abhijit R., Thakur, Ganesh A.
Pubblicazione 2013

Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target

di Janero, David R., Thakur, Ganesh A.
Pubblicato in Expert Opin Drug Discov (2016)

Conformationally constrained analogs of BAY 59–3074 as novel cannabinoid receptor ligands

di Teng, Heidi, Thakur, Ganesh A., Makriyannis, Alexandros
Pubblicazione 2011

Synthesis, Characterization, and Antibacterial Studies of Mixed Ligand Dioxouranium Complexes with 8-Hydroxyquinoline and Some Amino Acids

di Patil, Sunil S., Thakur, Ganesh A., Shaikh, Manzoor M.
Pubblicazione 2011

Mapping the Structural Requirements in the CB(1) Cannabinoid Receptor Transmembrane Helix II for Signal Transduction

di Kapur, Ankur, Samaniego, Patrick, Thakur, Ganesh A., Makriyannis, Alexandros, Abood, Mary E.
Pubblicazione 2008

Expeditious Synthesis, Enantiomeric Resolution and Enantiomer Functional Characterization of (4-(4-bromophenyl)-3a, 4, 5, 9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP...

di Thakur, Ganesh A., Kulkarni, Abhijit R., Deschamps, Jeffrey R., Papke, Roger L.
Pubblicazione 2013

A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ(9)-THC in Rats

di Järbe, Torbjörn U.C., LeMay, Brian J., Thakur, Ganesh A., Makriyannis, Alexandros
Pubblicato in Pharmacol Biochem Behav (2016)

Analysis of Tolerance and Behavioral/Physical Dependence during Chronic CB(1) Agonist Treatment: Effects of CB(1) Agonists, Antagonists, and Noncannabinoid Drugs

di Desai, Rajeev I., Thakur, Ganesh A., Vemuri, V. Kiran, Bajaj, Shama, Makriyannis, Alexandros, Bergman, Jack
Pubblicazione 2013

Tolerance to the Diuretic Effects of Cannabinoids and Cross-Tolerance to a κ-Opioid Agonist in THC-Treated Mice

di Chopda, Girish R., Parge, Viraj, Thakur, Ganesh A., Gatley, S. John, Makriyannis, Alexandros, Paronis, Carol A.
Pubblicato in J Pharmacol Exp Ther (2016)

Some Effects of CB1 Antagonists with Inverse Agonist and Neutral Biochemical Properties,

di Bergman, Jack, Delatte, Marcus. S., Paronis, Carol A., Vemuri, Kiran, Pandarinathan, Pathi, Thakur, Ganesh A., Makriyannis, Alex
Pubblicazione 2007

Diuretic effects of cannabinoid agonists in mice

di Chopda, Girish R, Vemuri, V Kiran, Sharma, Rishi, Thakur, Ganesh A, Makriyannis, Alexandros, Paronis, Carol A
Pubblicazione 2013

B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation

di Garai, Sumanta, Raja, Krishnamohan S., Papke, Roger L., Deschamps, Jeffrey R., Damaj, M. Imad, Thakur, Ganesh A.
Pubblicato in ACS Med Chem Lett (2018)

Selective Activation of Cannabinoid CB(2) Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

di Rahn, Elizabeth J., Zvonok, Alexander M., Thakur, Ganesh A., Khanolkar, Atmaram D., Makriyannis, Alexandros, Hohmann, Andrea G.
Pubblicazione 2008

Pharmacological characterization of AM1710, a putative cannabinoid CB(2) agonist from the cannabilactone class: Antinociception without central nervous system side-effects

di Rahn, Elizabeth J., Thakur, Ganesh A., Wood, JodiAnne T., Zvonok, Alexander M., Makriyannis, Alexandros, Hohmann, Andrea G.
Pubblicazione 2011

Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and...

di Quadri, Marta, Garai, Sumanta, Thakur, Ganesh A., Stokes, Clare, Gulsevin, Alican, Horenstein, Nicole A., Papke, Roger L.
Pubblicato in Mol Pharmacol (2019)

Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site

di Gulsevin, Alican, Papke, Roger L., Stokes, Clare, Garai, Sumanta, Thakur, Ganesh A., Quadri, Marta, Horenstein, Nicole A.
Pubblicato in Mol Pharmacol (2019)

Identification of CB1 Receptor Allosteric Sites Using Force-Biased MMC Simulated Annealing and Validation by Structure–Activity Relationship Studies

di Hurst, Dow P., Garai, Sumanta, Kulkarni, Pushkar M., Schaffer, Peter C., Reggio, Patricia H., Thakur, Ganesh A.
Pubblicato in ACS Med Chem Lett (2019)

C3-Heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor

di Dixon, Darryl D., Tius, Marcus A., Thakur, Ganesh A., Shukla, Vidyanand G., Zhou, Han, Peng, Yan, Makriyannis, Alexandros
Pubblicazione 2012

The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB(2) receptor activation and independent of CXCR4 signaling in mode...

di Deng, Liting, Guindon, Josée, Vemuri, V Kiran, Thakur, Ganesh A, White, Fletcher A, Makriyannis, Alexandros, Hohmann, Andrea G
Pubblicazione 2012