A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ(9)-THC in Rats

In addition to endogenous lipids, the two main cloned receptors (CB(1)R and CB(2)R) of the endocannabinoid signaling system (ECS) can be activated (and blocked) by various exogenous ligands. A relatively novel template for CB(1)R activators contains an adamantyl moiety as a key structural subunit, t...

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Vydáno v:Pharmacol Biochem Behav
Hlavní autoři: Järbe, Torbjörn U.C., LeMay, Brian J., Thakur, Ganesh A., Makriyannis, Alexandros
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972635/
https://ncbi.nlm.nih.gov/pubmed/27264437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2016.06.001
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