A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ(9)-THC in Rats

In addition to endogenous lipids, the two main cloned receptors (CB(1)R and CB(2)R) of the endocannabinoid signaling system (ECS) can be activated (and blocked) by various exogenous ligands. A relatively novel template for CB(1)R activators contains an adamantyl moiety as a key structural subunit, t...

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Detaylı Bibliyografya
Yayımlandı:Pharmacol Biochem Behav
Asıl Yazarlar: Järbe, Torbjörn U.C., LeMay, Brian J., Thakur, Ganesh A., Makriyannis, Alexandros
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972635/
https://ncbi.nlm.nih.gov/pubmed/27264437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2016.06.001
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