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Tolerance to the Diuretic Effects of Cannabinoids and Cross-Tolerance to a κ-Opioid Agonist in THC-Treated Mice

Daily treatment with cannabinoids results in tolerance to many, but not all, of their behavioral and physiologic effects. The present studies investigated the effects of 7-day exposure to 10 mg/kg daily of Δ(9)-tetrahydrocannabinol (THC) on the diuretic and antinociceptive effects of THC and the syn...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Chopda, Girish R., Parge, Viraj, Thakur, Ganesh A., Gatley, S. John, Makriyannis, Alexandros, Paronis, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959092/
https://ncbi.nlm.nih.gov/pubmed/27231154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232132
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