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C3-Heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor
A series of tricyclic cannabinoids incorporating a heteroaroyl group at C3 were prepared as probes to explore the binding site(s) of the CB1 and CB2 receptors. This relatively unexplored structural motif is shown to be CB2 selective with K(i) values at low nanomolar concentrations when the heteroaro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445631/ https://ncbi.nlm.nih.gov/pubmed/22796181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.06.013 |
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