Cannabinoid Discrimination and Antagonism by CB(1) Neutral and Inverse Agonist Antagonists

Cannabinoid receptor 1 (CB(1)) inverse agonists (e.g., rimonabant) have been reported to produce adverse effects including nausea, emesis, and anhedonia that limit their clinical applications. Recent laboratory studies suggest that the effects of CB(1) neutral antagonists differ from those of such i...

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Bibliografiska uppgifter
Huvudupphovsmän: Kangas, Brian D., Delatte, Marcus S., Vemuri, V. Kiran, Thakur, Ganesh A., Nikas, Spyridon P., Subramanian, Kumara V., Shukla, Vidyanand G., Makriyannis, Alexandros, Bergman, Jack
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2013
Ämnen:
Behavioral Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583508/
https://ncbi.nlm.nih.gov/pubmed/23287700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201962
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