Cannabinoid Discrimination and Antagonism by CB(1) Neutral and Inverse Agonist Antagonists

Cannabinoid receptor 1 (CB(1)) inverse agonists (e.g., rimonabant) have been reported to produce adverse effects including nausea, emesis, and anhedonia that limit their clinical applications. Recent laboratory studies suggest that the effects of CB(1) neutral antagonists differ from those of such i...

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Detalhes bibliográficos
Main Authors: Kangas, Brian D., Delatte, Marcus S., Vemuri, V. Kiran, Thakur, Ganesh A., Nikas, Spyridon P., Subramanian, Kumara V., Shukla, Vidyanand G., Makriyannis, Alexandros, Bergman, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583508/
https://ncbi.nlm.nih.gov/pubmed/23287700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201962
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