Cannabinoid Discrimination and Antagonism by CB(1) Neutral and Inverse Agonist Antagonists

Cannabinoid receptor 1 (CB(1)) inverse agonists (e.g., rimonabant) have been reported to produce adverse effects including nausea, emesis, and anhedonia that limit their clinical applications. Recent laboratory studies suggest that the effects of CB(1) neutral antagonists differ from those of such i...

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Main Authors: Kangas, Brian D., Delatte, Marcus S., Vemuri, V. Kiran, Thakur, Ganesh A., Nikas, Spyridon P., Subramanian, Kumara V., Shukla, Vidyanand G., Makriyannis, Alexandros, Bergman, Jack
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2013
主題:
Behavioral Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583508/
https://ncbi.nlm.nih.gov/pubmed/23287700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201962
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