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Novel Adamantyl Cannabinoids as CB1 Receptor Probes

In previous studies compound 1 (AM411), a 3-(1-adamantyl) analog of the phytocannabinoid (−)-Δ(8)-tetrahydrocannabinol (Δ(8)-THC) was shown to have improved affinity and selectivity for the CB1 receptor. In this work, we further explored the role of the 1-adamantyl group at the C-3 position in a ser...

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Detalhes bibliográficos
Main Authors: Thakur, Ganesh A., Bajaj, Shama, Paronis, Carol, Peng, Yan, Bowman, Anna L., Barak, Lawrence S., Caron, Marc G., Parrish, Demon, Deschamps, Jeffrey R., Makriyannis, Alexandros
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706088/
https://ncbi.nlm.nih.gov/pubmed/23621789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4000775
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