Recent Progress in the Discovery and Development of 2-Nitroimidazooxazines and 6-Nitroimidazooxazoles to Treat Tuberculosis and Neglected Tropical Diseases †

অনুযায়ী Showalter, Hollis D.
প্রকাশিত Molecules (2020)

A concise synthesis of 3-substituted-7-amino-6-carboxyl-8-azachromones

অনুযায়ী Gan, Xinmin, Showalter, Hollis D.
প্রকাশিত Tetrahedron Lett (2019)

Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometry()

অনুযায়ী Hagen, Susan E., Liu, Kun, Jin, Yafei, Piersimoni, Lolita, Andrews, Philip C., Showalter, Hollis D.
প্রকাশিত Org Biomol Chem (2018)

Design, Synthesis, and Biological Activity of 5′-Phenyl-1,2,5,6-tetrahydro-3,3′-bipyridine Analogues as Potential Antagonists of Nicotinic Acetylcholine Receptors

অনুযায়ী Jin, Yafei, Huang, Xiaoqin, Papke, Roger L., Jutkiewicz, Emily M., Showalter, Hollis D., Zhan, Chang-Guo
প্রকাশিত Bioorg Med Chem Lett (2017)

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C

অনুযায়ী Carpenter, Colleen, Sorenson, Roderick J., Jin, Yafei, Klossowski, Szymon, Cierpicki, Tomascz, Gnegy, Margaret, Showalter, Hollis D.
প্রকাশিত Bioorg Med Chem (2016)

Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

অনুযায়ী Perry, Jeffrey W., Ahmed, Mohammad, Chang, Kyeong-Ok, Donato, Nicholas J., Showalter, Hollis D., Wobus, Christiane E.
প্রকাশিত 2012

RecO and RecR Are Necessary for RecA Loading in Response to DNA Damage and Replication Fork Stress

অনুযায়ী Lenhart, Justin S., Brandes, Eileen R., Schroeder, Jeremy W., Sorenson, Roderick J., Showalter, Hollis D., Simmons, Lyle A.
প্রকাশিত 2014

Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine...

অনুযায়ী Chen, Yi-Chen, Brooks, Allen F., Goodenough-Lashua, DeeAnne M., Kittendorf, Jeffrey D., Showalter, Hollis D., Garcia, George A.
প্রকাশিত 2011

Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses

অনুযায়ী Charbonneau, Marie-Eve, Passalacqua, Karla D., Hagen, Susan E., Showalter, Hollis D., Wobus, Christiane E., O’Riordan, Mary X. D.
প্রকাশিত Sci Rep (2019)

Small Molecule Deubiquitinase Inhibitors Promote Macrophage Anti-Infective Capacity

অনুযায়ী Charbonneau, Marie-Eve, Gonzalez-Hernandez, Marta J., Showalter, Hollis D., Donato, Nicholas J., Wobus, Christiane E., O’Riordan, Mary X. D.
প্রকাশিত 2014

A Small Molecule Deubiquitinase Inhibitor Increases Localization of Inducible Nitric Oxide Synthase to the Macrophage Phagosome and Enhances Bacterial Killing

অনুযায়ী Burkholder, Kristin M., Perry, Jeffrey W., Wobus, Christiane E., Donato, Nicholas J., Showalter, Hollis D., Kapuria, Vaibhav, O'Riordan, Mary X. D.
প্রকাশিত 2011

Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects

অনুযায়ী Carpenter, Colleen, Zestos, Alexander G, Altshuler, Rachel, Sorenson, Roderick J, Guptaroy, Bipasha, Showalter, Hollis D, Kennedy, Robert T, Jutkiewicz, Emily, Gnegy, Margaret E
প্রকাশিত Neuropsychopharmacology (2017)

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition

অনুযায়ী Beyett, Tyler S., Gan, Xinmin, Reilly, Shannon M., Chang, Louise, Gomez, Andrew V., Saltiel, Alan R., Showalter, Hollis D., Tesmer, John J. G.
প্রকাশিত Mol Pharmacol (2018)

Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and...

অনুযায়ী Beyett, Tyler S., Gan, Xinmin, Reilly, Shannon M., Gomez, Andrew V., Chang, Louise, Tesmer, John J. G., Saltiel, Alan R., Showalter, Hollis D.
প্রকাশিত Bioorg Med Chem (2018)

Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

অনুযায়ী Gonzalez-Hernandez, Marta J., Pal, Anupama, Gyan, Kofi E., Charbonneau, Marie-Eve, Showalter, Hollis D., Donato, Nicholas J., O'Riordan, Mary, Wobus, Christiane E.
প্রকাশিত 2014

Substrate-competitive activity-based profiling of ester prodrug activating enzymes

অনুযায়ী Xu, Hao, Majmudar, Jaimeen D., Davda, Dahvid, Ghanakota, Phani, Kim, Ki H., Carlson, Heather A., Showalter, Hollis D., Martin, Brent R., Amidon, Gordon L.
প্রকাশিত Mol Pharm (2015)

Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat and human microsomes

অনুযায়ী Gan, Xinmin, Wilson, Michael W., Beyett, Tyler S., Wen, Bo, Sun, Duxin, Larsen, Scott D., Tesmer, John J. G., Saltiel, Alan R., Showalter, Hollis D.
প্রকাশিত J Labelled Comp Radiopharm (2019)

Lipid Storage Disorders Block Lysosomal Trafficking By Inhibiting TRP Channel and Calcium Release

অনুযায়ী Shen, Dongbiao, Wang, Xiang, Li, Xinran, Zhang, Xiaoli, Yao, Zepeng, Dibble, Shannon, Dong, Xian-ping, Yu, Ting, Lieberman, Andrew P., Showalter, Hollis D., Xu, Haoxing
প্রকাশিত 2012

Use of Enterally Delivered Angiotensin II Type Ia Receptor Antagonists to Reduce the Severity of Colitis

অনুযায়ী Okawada, Manabu, Koga, Hiroyuki, Larsen, Scott D., Showalter, Hollis D., Turbiak, Anjanette J., Jin, Xiaohong, Lucas, Peter C., Lipka, Elke, Hillfinger, John, Kim, Jae Seung, Teitelbaum, Daniel H.
প্রকাশিত 2011

Menin-MLL Inhibitors Reverse Oncogenic Activity of MLL Fusion Proteins in Leukemia

অনুযায়ী Grembecka, Jolanta, He, Shihan, Shi, Aibin, Purohit, Trupta, Muntean, Andrew G., Sorenson, Roderick J., Showalter, Hollis D., Murai, Marcelo, Belcher, Amalia, Hartley, Thomas, Hess, Jay L., Cierpicki, Tomasz
প্রকাশিত 2012