Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects

Amphetamines (AMPHs) are globally abused. With no effective treatment for AMPH addiction to date, there is urgent need for the identification of druggable targets that mediate the reinforcing action of this stimulant class. AMPH-stimulated dopamine efflux is modulated by protein kinase C (PKC) activ...

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發表在:Neuropsychopharmacology
Main Authors: Carpenter, Colleen, Zestos, Alexander G, Altshuler, Rachel, Sorenson, Roderick J, Guptaroy, Bipasha, Showalter, Hollis D, Kennedy, Robert T, Jutkiewicz, Emily, Gnegy, Margaret E
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561350/
https://ncbi.nlm.nih.gov/pubmed/28492278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.95
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