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Tamoxifen Directly Interacts with the Dopamine Transporter
The selective estrogen receptor modulator tamoxifen increases extracellular dopamine in vivo and acts as a neuroprotectant in models of dopamine neurotoxicity. We investigated the effect of tamoxifen on dopamine transporter (DAT)–mediated dopamine uptake, dopamine efflux, and [(3)H]WIN 35,428 [(–)-2...
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| Publicado en: | J Pharmacol Exp Ther |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7250473/ https://ncbi.nlm.nih.gov/pubmed/30108161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.248179 |
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