Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions. A good strategy for circumventing drug resistance, or for pathogens without treatment options, is to target host cell proteins that a...

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Autori principali: Gonzalez-Hernandez, Marta J., Pal, Anupama, Gyan, Kofi E., Charbonneau, Marie-Eve, Showalter, Hollis D., Donato, Nicholas J., O'Riordan, Mary, Wobus, Christiane E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983190/
https://ncbi.nlm.nih.gov/pubmed/24722666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094491
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