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RecO and RecR Are Necessary for RecA Loading in Response to DNA Damage and Replication Fork Stress

RecA is central to maintaining genome integrity in bacterial cells. Despite the near-ubiquitous conservation of RecA in eubacteria, the pathways that facilitate RecA loading and repair center assembly have remained poorly understood in Bacillus subtilis. Here, we show that RecA rapidly colocalizes w...

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Detalhes bibliográficos
Main Authors: Lenhart, Justin S., Brandes, Eileen R., Schroeder, Jeremy W., Sorenson, Roderick J., Showalter, Hollis D., Simmons, Lyle A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135682/
https://ncbi.nlm.nih.gov/pubmed/24891441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01494-14
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