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RecO and RecR Are Necessary for RecA Loading in Response to DNA Damage and Replication Fork Stress

RecA is central to maintaining genome integrity in bacterial cells. Despite the near-ubiquitous conservation of RecA in eubacteria, the pathways that facilitate RecA loading and repair center assembly have remained poorly understood in Bacillus subtilis. Here, we show that RecA rapidly colocalizes w...

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Main Authors: Lenhart, Justin S., Brandes, Eileen R., Schroeder, Jeremy W., Sorenson, Roderick J., Showalter, Hollis D., Simmons, Lyle A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135682/
https://ncbi.nlm.nih.gov/pubmed/24891441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01494-14
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