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Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometry()

Two novel cyclic quaternary amine crosslinking probes are synthesized for structural mass spectrometry of protein complexes in solution and for analysis of protein interactions in organellar and whole cell extracts. Each exhibits high aqueous solubility, excellent protein crosslinking efficiencies,...

詳細記述

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書誌詳細
出版年:Org Biomol Chem
主要な著者: Hagen, Susan E., Liu, Kun, Jin, Yafei, Piersimoni, Lolita, Andrews, Philip C., Showalter, Hollis D.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138586/
https://ncbi.nlm.nih.gov/pubmed/29537042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00329g
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