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Synthesis of CID-cleavable protein crosslinking agents containing quaternary amines for structural mass spectrometry()

Two novel cyclic quaternary amine crosslinking probes are synthesized for structural mass spectrometry of protein complexes in solution and for analysis of protein interactions in organellar and whole cell extracts. Each exhibits high aqueous solubility, excellent protein crosslinking efficiencies,...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Hagen, Susan E., Liu, Kun, Jin, Yafei, Piersimoni, Lolita, Andrews, Philip C., Showalter, Hollis D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138586/
https://ncbi.nlm.nih.gov/pubmed/29537042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00329g
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