Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma

nork Herrero-Martin, David, Fourtouna, Argyro, Niedan, Stephan, Riedmann, Lucia T., Schwentner, Raphaela, Aryee, Dave N. T.
Argitaratua 2011

EWS-FLI1 employs an E2F switch to drive target gene expression

nork Schwentner, Raphaela, Papamarkou, Theodore, Kauer, Maximilian O., Stathopoulos, Vassilios, Yang, Fan, Bilke, Sven, Meltzer, Paul S., Girolami, Mark, Kovar, Heinrich
Argitaratua izan da Nucleic Acids Res (2015)

Vemurafenib in Langerhans cell histiocytosis: report of a pediatric patient and review of the literature

nork Heisig, Anne, Sörensen, Jan, Zimmermann, Stefanie-Yvonne, Schöning, Stefan, Schwabe, Dirk, Kvasnicka, Hans-Michael, Schwentner, Raphaela, Hutter, Caroline, Lehrnbecher, Thomas
Argitaratua izan da Oncotarget (2018)

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

nork Schwentner, Raphaela, Herrero-Martin, David, Kauer, Maximilian O, Mutz, Cornelia N, Katschnig, Anna M, Sienski, Grzegorz, Alonso, Javier, Aryee, Dave NT, Kovar, Heinrich
Argitaratua izan da Oncotarget (2016)

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer

nork Bilke, Sven, Schwentner, Raphaela, Yang, Fan, Kauer, Maximilian, Jug, Gunhild, Walker, Robert L., Davis, Sean, Zhu, Yuelin J., Pineda, Marbin, Meltzer, Paul S., Kovar, Heinrich
Argitaratua 2013

Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs

nork Svoboda, Laurie K, Harris, Ashley, Bailey, Natashay J, Schwentner, Raphaela, Tomazou, Eleni, von Levetzow, Cornelia, Magnuson, Brian, Ljungman, Mats, Kovar, Heinrich, Lawlor, Elizabeth R
Argitaratua izan da Epigenetics (2015)

EWS-FLI1 Suppresses NOTCH-Activated p53 in Ewing’s Sarcoma

nork Ban, Jozef, Bennani-Baiti, Idriss M., Kauer, Max, Schaefer, Karl-Ludwig, Poremba, Christopher, Jug, Gunhild, Schwentner, Raphaela, Smrzka, Oskar, Muehlbacher, Karin, Aryee, Dave N.T., Kovar, Heinrich
Argitaratua izan da Cancer Res (2008)

EWS‐FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway

nork Mutz, Cornelia N., Schwentner, Raphaela, Kauer, Maximilian O., Katschnig, Anna M., Kromp, Florian, Aryee, Dave N. T., Erhardt, Sophie, Goiny, Michel, Alonso, Javier, Fuchs, Dietmar, Kovar, Heinrich
Argitaratua izan da FEBS Lett (2016)

Targeted inhibition of the MAPK pathway: emerging salvage option for progressive life-threatening multisystem LCH

nork Kolenová, Alexandra, Schwentner, Raphaela, Jug, Gunhild, Simonitsch-Klupp, Ingrid, Kornauth, Christoph, Plank, Lukáš, Horáková, Júlia, Bodová, Ivana, Sýkora, Tomáš, Geczová, Lucia, Holter, Wolfgang, Minkov, Milen, Hutter, Caroline
Argitaratua izan da Blood Adv (2017)

Hypoxia modulates EWS-FLI1 transcriptional signature and enhances malignant properties of Ewing's sarcoma cells in-vitro

nork Aryee, Dave N.T., Niedan, Stephan, Kauer, Maximilian, Schwentner, Raphaela, Bennani-Baiti, Idriss M., Ban, Jozef, Muehlbacher, Karin, Kreppel, Michael, Walker, Robert L., Meltzer, Paul, Poremba, Christopher, Kofler, Reinhard, Kovar, Heinrich
Argitaratua 2010

Hsa-mir-145 is the top EWS-FLI1 repressed microRNA involved in a positive feed-back loop in Ewing’s sarcoma

nork Ban, Jozef, Jug, Gunhild, Mestdagh, Pieter, Schwentner, Raphaela, Kauer, Max, Aryee, Dave N.T., Schaefer, Karl-Ludwig, Nakatani, Fumihiko, Scotlandi, Katia, Reiter, Marlies, Strunk, Dirk, Speleman, Frank, Vandesompele, Jo, Kovar, Heinrich
Argitaratua izan da Oncogene (2011)

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells

nork Mutz, Cornelia N., Schwentner, Raphaela, Aryee, Dave N.T., Bouchard, Eric D.J., Mejia, Edgard M., Hatch, Grant M., Kauer, Maximilian O., Katschnig, Anna M., Ban, Jozef, Garten, Antje, Alonso, Javier, Banerji, Versha, Kovar, Heinrich
Argitaratua izan da Oncotarget (2017)

Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis

nork Halbritter, Florian, Farlik, Matthias, Schwentner, Raphaela, Jug, Gunhild, Fortelny, Nikolaus, Schnöller, Thomas, Pisa, Hanja, Schuster, Linda C., Reinprecht, Andrea, Czech, Thomas, Gojo, Johannes, Holter, Wolfgang, Minkov, Milen, Bauer, Wolfgang, Simonitsch-Klupp, Ingrid, Bock, Christoph, Hutter, Caroline
Argitaratua izan da Cancer Discov (2019)

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

nork Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich
Argitaratua izan da Oncogenesis (2021)

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

nork Tsafou, Kalliopi, Katschnig, Anna Maria, Radic-Sarikas, Branka, Mutz, Cornelia Noëlle, Iljin, Kristiina, Schwentner, Raphaela, Kauer, Maximilian O., Mühlbacher, Karin, Aryee, Dave N.T., Westergaard, David, Haapa-Paananen, Saija, Fey, Vidal, Superti-Furga, Giulio, Toretsky, Jeffrey, Brunak, Søren, Kovar, Heinrich
Argitaratua izan da Oncotarget (2018)

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

nork van der Lelij, Petra, Lieb, Simone, Jude, Julian, Wutz, Gordana, Santos, Catarina P, Falkenberg, Katrina, Schlattl, Andreas, Ban, Jozef, Schwentner, Raphaela, Hoffmann, Thomas, Kovar, Heinrich, Real, Francisco X, Waldman, Todd, Pearson, Mark A, Kraut, Norbert, Peters, Jan-Michael, Zuber, Johannes, Petronczki, Mark
Argitaratua izan da eLife (2017)

The First European Interdisciplinary Ewing Sarcoma Research Summit

nork Kovar, Heinrich, Alonso, Javier, Aman, Pierre, Aryee, Dave N. T., Ban, Jozef, Burchill, Sue A., Burdach, Stefan, De Alava, Enrique, Delattre, Olivier, Dirksen, Uta, Fourtouna, Argyro, Fulda, Simone, Helman, Lee J., Herrero-Martin, David, Hogendoorn, Pancras C. W., Kontny, Udo, Lawlor, Elizabeth R., Lessnick, Stephen L., Llombart-Bosch, Antonio, Metzler, Markus, Moriggl, Richard, Niedan, Stephan, Potratz, Jenny, Redini, Françoise, Richter, Günther H. S., Riedmann, Lucia T., Rossig, Claudia, Schäfer, Beat W., Schwentner, Raphaela, Scotlandi, Katia, Sorensen, Poul H., Staege, Martin S., Tirode, Franck, Toretsky, Jeffrey, Ventura, Selena, Eggert, Angelika, Ladenstein, Ruth
Argitaratua 2012