Innate Immune sensing of DNA viruses

Por Rathinam, Vijay A. K., Fitzgerald, Katherine A.
Publicado em 2011

Dendritic cells from C57BL/6 mice undergo activation and induce Th1-effector cell responses against Campylobacter jejuni

Por Rathinam, Vijay A.K., Hoag, Kathleen A., Mansfield, Linda S.
Publicado em 2008

Regulation of inflammasome signaling

Por Rathinam, Vijay A K, Vanaja, Sivapriya Kailasan, Fitzgerald, Katherine A
Publicado em 2012

Campylobacter jejuni-Induced Activation of Dendritic Cells Involves Cooperative Signaling through Toll-Like Receptor 4 (TLR4)-MyD88 and TLR4-TRIF Axes

Por Rathinam, Vijay A. K., Appledorn, Daniel M., Hoag, Kathleen A., Amalfitano, Andrea, Mansfield, Linda S.
Publicado em 2009

Aim2-deficiency stimulates the expression of interferon-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus

Por Panchanathan, Ravichandran, Duan, Xin, Shen, Hui, Rathinam, Vijay A. K., Erickson, Loren D., Fitzgerald, Katherine A, Choubey, Divaker
Publicado em 2010

Aim2-deficiency in mice suppresses the expression of the inhibitory Fcγ receptor (FcγRIIB) through the induction of the interferon-inducible p202, a lupus susceptibility protein

Por Panchanathan, Ravichandran, Shen, Hui, Duan, Xin, Rathinam, Vijay A. K., Erickson, Loren D., Fitzgerald, Katherine A., Choubey, Divaker
Publicado em 2011

Bacterial outer membrane vesicles mediate cytosolic localization of LPS and caspase-11 activation

Por Vanaja, Sivapriya Kailasan, Russo, Ashley J., Behl, Bharat, Banerjee, Ishita, Yankova, Maya, Deshmukh, Sachin D., Rathinam, Vijay A.K.
Publicado no Cell (2016)

Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome

Por Kailasan Vanaja, Sivapriya, Rathinam, Vijay A. K., Atianand, Maninjay K., Kalantari, Parisa, Skehan, Brian, Fitzgerald, Katherine A., Leong, John M.
Publicado em 2014

Inflammation in Mice Ectopically Expressing Human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T Mutant Proteins

Por Wang, Donghai, Höing, Susanne, Patterson, Heide Christine, Ahmad, Umtul M., Rathinam, Vijay A. K., Rajewsky, Klaus, Fitzgerald, Katherine A., Golenbock, Douglas T.
Publicado em 2013

Nitric oxide controls tuberculosis immunopathology by inhibiting NLRP3 inflammasome-dependent IL-1β processing

Por Mishra, Bibhuti B., Rathinam, Vijay A. K., Martens, Gregory W., Martinot, Amanda J., Kornfeld, Hardy, Fitzgerald, Katherine A., Sassetti, Christopher M.
Publicado em 2012

Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

Por Bueter, Chelsea L., Lee, Chrono K., Rathinam, Vijay A. K., Healy, Gloria J., Taron, Christopher H., Specht, Charles A., Levitz, Stuart M.
Publicado em 2011

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Por Rathinam, Vijay A.K., Vanaja, Sivapriya Kailasan, Waggoner, Lisa, Sokolovska, Anna, Becker, Christine, Stuart, Lynda M., Leong, John M., Fitzgerald, Katherine A.
Publicado em 2012

Mycobacterium tuberculosis but not non-virulent mycobacteria inhibit IFN-β and AIM2-inflammasome dependent IL-1β production via their ESX-1 secretion system

Por Shah, Swati, Bohsali, Amro, Ahlbrand, Sarah E., Srinivasan, Lalitha, Rathinam, Vijay A. K., Vogel, Stefanie N., Fitzgerald, Katherine A., Sutterwala, Fayyaz S., Briken, Volker
Publicado em 2013

Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient mice

Por Wilson, David L., Rathinam, Vijay A. K., Qi, Weihong, Wick, Lukas M., Landgraf, Jeff, Bell, Julia A., Plovanich-Jones, Anne, Parrish, Jodi, Finley, Russell L., Mansfield, Linda S., Linz, John E.
Publicado em 2010

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent DMXAA

Por Conlon, Joseph, Burdette, Dara L., Sharma, Shruti, Bhat, Numana, Thompson, Mikayla, Jiang, Zhaozhao, Rathinam, Vijay A. K., Monks, Brian, Jin, Tengchuan, Xiao, T. Sam, Vogel, Stefanie N., Vance, Russell E., Fitzgerald, Katherine A.
Publicado em 2013

Overexpression of Membrane-bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-induced Lupus

Por Bossaller, Lukas, Rathinam, Vijay A.K., Bonegio, Ramon, Chiang, Ping-I, Busto, Patricia, Wespiser, Adam R., Caffrey, Daniel R., Li, Quan-Zhen, Mohan, Chandra, Fitzgerald, Katherine A., Latz, Eicke, Marshak-Rothstein, Ann
Publicado no J Immunol (2013)

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Por Sokolovska, Anna, Becker, Christine E., Eddie Ip, WK, Rathinam, Vijay A.K., Brudner, Matthew, Paquette, Nicholas, Tanne, Antoine, Vanaja, Sivapriya K., Moore, Kathryn J., Fitzgerald, Katherine A., Lacy-Hulbert, Adam, Stuart, Lynda M.
Publicado em 2013

FAS mediates non-canonical IL-1β and IL-18 maturation via caspase-8 in a Rip3-independent manner()

Por Bossaller, Lukas, Chiang, Ping-I, Schmidt-Lauber, Christian, Ganesan, Sandhya, Kaiser, William J., Rathinam, Vijay A.K., Mocarski, Edward S., Subramanian, Deepa, Green, Douglas R., Silverman, Neal, Fitzgerald, Katherine A., Marshak-Rothstein, Ann, Latz, Eicke
Publicado em 2012

Caspase-8 modulates Dectin-1 and CR3 driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans(1)

Por Ganesan, Sandhya, Rathinam, Vijay A. K., Bossaller, Lukas, Army, Kelly, Kaiser, William J., Mocarski, Edward S., Dillon, Christopher P., Green, Douglas R., Mayadas, Tanya N., Levitz, Stuart M., Hise, Amy G., Silverman, Neal, Fitzgerald, Katherine A.
Publicado em 2014

The AIM2 inflammasome is essential for host-defense against cytosolic bacteria and DNA viruses

Por Rathinam, Vijay A.K., Jiang, Zhaozhao, Waggoner, Stephen N., Sharma, Shruti, Cole, Leah E., Waggoner, Lisa, Vanaja, Sivapriya Kailasan, Monks, Brian G., Ganesan, Sandhya, Latz, Eicke, Hornung, Veit, Vogel, Stefanie N., Szomolanyi-Tsuda, Eva, Fitzgerald., Katherine A.
Publicado em 2010