FAS mediates non-canonical IL-1β and IL-18 maturation via caspase-8 in a Rip3-independent manner()

Fas, a tumor necrosis factor family receptor, is activated by the membrane protein Fas ligand (FasL) expressed on various immune cells. Fas signaling triggers apoptosis and induces inflammatory cytokine production. Among the Fas induced cytokines, the IL-1β family cytokines require proteolysis to ga...

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Detalhes bibliográficos
Main Authors: Bossaller, Lukas, Chiang, Ping-I, Schmidt-Lauber, Christian, Ganesan, Sandhya, Kaiser, William J., Rathinam, Vijay A.K., Mocarski, Edward S., Subramanian, Deepa, Green, Douglas R., Silverman, Neal, Fitzgerald, Katherine A., Marshak-Rothstein, Ann, Latz, Eicke
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518757/
https://ncbi.nlm.nih.gov/pubmed/23144495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202121
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