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Overexpression of Membrane-bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-induced Lupus
Loss of function mutations in the Fas death receptor or its ligand result in a lymphoproliferative syndrome and exacerbate clinical disease in most lupus-prone strains of mice. One exception is mice injected with 2,6,10,14-Tetramethylpentadecane (TMPD), a hydrocarbon oil commonly known as pristane,...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4219920/ https://ncbi.nlm.nih.gov/pubmed/23918976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300341 |
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