Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis

BACKGROUND: An altered susceptibility of lung fibroblasts to Fas-induced apoptosis has been implicated in the pathogenesis of pulmonary fibrosis; however, the underlying mechanism is not completely understood. Here, we studied the susceptibility of lung fibroblasts, obtained from patients with (f-fi...

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Detalhes bibliográficos
Main Authors: Bühling, Frank, Wille, Aline, Röcken, Christoph, Wiesner, Olaf, Baier, Anja, Meinecke, Ingmar, Welte, Tobias, Pap, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087885/
https://ncbi.nlm.nih.gov/pubmed/15833141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-37
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