Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent

INTRODUCTION: The rheumatoid arthritis (RA) synovium is characterised by the presence of an aggressive population of activated synovial fibroblasts (RASFs) that are prominently involved in the destruction of articular cartilage and bone. Accumulating evidence suggests that RASFs are relatively resis...

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Main Authors: Pundt, Noreen, Peters, Marvin A, Wunrau, Christina, Strietholt, Simon, Fehrmann, Carsten, Neugebauer, Katja, Seyfert, Christine, van Valen, Frans, Pap, Thomas, Meinecke, Ingmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688248/
https://ncbi.nlm.nih.gov/pubmed/19196465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2607
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