TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus

Systemic lupus erythematosus (SLE) is a chronic, life threatening autoimmune disorder, leading to multiple organ pathologies and kidney destruction. Analyses of numerous murine models of spontaneous SLE have revealed a critical role for endosomal Toll-like receptors (TLRs) in the production of autoa...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bossaller, Lukas, Christ, Anette, Pelka, Karin, Nundel, Kerstin, Chiang, Ping-I, Pang, Catherine, Mishra, Neha, Busto, Patricia, Bonegio, Ramon G, Schmidt, Reinhold Ernst, Latz, Eicke, Marshak-Rothstein, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266544/
https://ncbi.nlm.nih.gov/pubmed/27354219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501943
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