Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?

Both endosomal and cytosolic-nucleic acid–sensing receptors can detect endogenous ligands and promote autoimmunity and autoinflammation. These responses involve a complex interplay among and between the cytosolic and endosomal sensors involving both hematopoietic and radioresistant cells. Cytosolic...

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Vydáno v:J Leukoc Biol
Hlavní autoři: Pawaria, Sudesh, Sharma, Shruti, Baum, Rebecca, Nündel, Kerstin, Busto, Patricia, Gravallese, Ellen M., Fitzgerald, Katherine A., Marshak-Rothstein, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166439/
https://ncbi.nlm.nih.gov/pubmed/27531928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3MR0316-115R
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