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Synergy between Hematopoietic and Radioresistant Stromal Cells is Required for Autoimmune Manifestations of DNase II(−/−) IFNaR(−/−) Mice
Detection of endogenous nucleic acids by cytosolic receptors, dependent on STING, and endosomal sensors, dependent on Unc93b1, can provoke inflammatory responses that contribute to a variety of autoimmune and autoinflammatory diseases. In DNase II deficient mice, the excessive accrual of undegraded...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724517/ https://ncbi.nlm.nih.gov/pubmed/26729810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502130 |
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