Synergy between Hematopoietic and Radioresistant Stromal Cells is Required for Autoimmune Manifestations of DNase II(−/−) IFNaR(−/−) Mice

Detection of endogenous nucleic acids by cytosolic receptors, dependent on STING, and endosomal sensors, dependent on Unc93b1, can provoke inflammatory responses that contribute to a variety of autoimmune and autoinflammatory diseases. In DNase II deficient mice, the excessive accrual of undegraded...

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Vydáno v:J Immunol
Hlavní autoři: Baum, Rebecca, Nündel, Kerstin, Pawaria, Sudesh, Sharma, Shruti, Busto, Patricia, Fitzgerald, Katherine A., Gravallese, Ellen M., Marshak-Rothstein, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724517/
https://ncbi.nlm.nih.gov/pubmed/26729810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502130
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