Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency

Nucleic acid (NA) sensing receptors were first described in the context of host defense. We now know that some endosomal NA sensors play a critical role in the development of systemic autoimmune diseases such as systemic lupus erythematosus, whereas cytosolic Cyclic GMP-AMP Synthase/Stimulator of IF...

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Publicado en:Viral Immunol
Autores principales: Marshak-Rothstein, Ann, Manning, Catherine A., Baum, Rebecca, Pawaria, Sudesh, Gravallese, Ellen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185368/
https://ncbi.nlm.nih.gov/pubmed/32286184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2019.0191
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