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Nucleic Acid Sensing Receptors – Rheostats of Autoimmunity and Autoinflammation

Distinct families of germline encoded pattern recognition receptors can sense both microbial and endogenous nucleic acids. These DNA and RNA sensors include endosomal TLRs and cytosolic sensors upstream of STING and MAVS. The existence of overlapping specificities for both foreign and self nucleic a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Sharma, Shruti, Fitzgerald, Katharine A., Cancro, Michael P., Marshak-Rothstein, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593056/
https://ncbi.nlm.nih.gov/pubmed/26432899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500964
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