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Nucleic Acid Sensing Receptors – Rheostats of Autoimmunity and Autoinflammation

Distinct families of germline encoded pattern recognition receptors can sense both microbial and endogenous nucleic acids. These DNA and RNA sensors include endosomal TLRs and cytosolic sensors upstream of STING and MAVS. The existence of overlapping specificities for both foreign and self nucleic a...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Sharma, Shruti, Fitzgerald, Katharine A., Cancro, Michael P., Marshak-Rothstein, Ann
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593056/
https://ncbi.nlm.nih.gov/pubmed/26432899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500964
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