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Nucleic Acid Sensing Receptors – Rheostats of Autoimmunity and Autoinflammation
Distinct families of germline encoded pattern recognition receptors can sense both microbial and endogenous nucleic acids. These DNA and RNA sensors include endosomal TLRs and cytosolic sensors upstream of STING and MAVS. The existence of overlapping specificities for both foreign and self nucleic a...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593056/ https://ncbi.nlm.nih.gov/pubmed/26432899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500964 |
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